What is a Chronic Immune Disorder?

Most people with a chronic disease don’t know that they probably have a Chronic Immune Disorder (CID) But what is a CID? If you have a CID your immune system chronically dysfunctions which can lead to numerous diseases.

First of all it is important to have an overview of which diseases have correlation with the immune system. There are quite a few, chronic diseases in particular. See the chart below for a few examples. All these diseases seem different but in fact have one underlying mechanism. The immune system plays an important role when it involves a chronically dysfunctioning of the immune system that causes the disease, preserves it or when it is incapable of fighting it. Generally speaking, there are four categories of Chronic Immune Disorders:

  • The defence mechanism is too strong and targets the inner body (auto immune disorders)
  • The defence mechanism is too strong and targets the external body (allergies)
  • The defence mechanism is too weak and insufficiently targets the inner body (not detecting nor eliminating deficient cells like cancer)
  • The defence mechanism is too weak and insufficiently targets the external body (immune deficiency in diseases like AIDS)

Table below is not complete; it will be updated over time.

Too strong, inner body
Too strong, external body
Too weak, inner body
Too weak, external body

Multiple Sclerosis

Graves’ Disease

Reumatoid Artritis

Wegener’s Disease

Chronic Eosinophilic Pneumonia

Crohn e.o. IBD


Alzheimer (probably)

Parkinson (probably)



SLE (Lupus)






Various Cancer





X-linked agammaglobulinemia (XLA)

Common variable immunodeficiency (CVID)

Severe combined immunodeficiency (SCID)

Viral Hepatitis


More details about some disorders in the table above


The immune system fails when trying to eliminate the plaques (type of protein) that block the transmission of information messages between neurons. This might negatively affect the capacity for thought and memory. The immune system might also, probably wrongfully, eliminate specific brain cells and/or might cause the plaques itself.

Source: hersenstichting.nl, c2w.nl (brain foundation)


(Most probably) immune cells eliminate specific brain cells, causing the brain to stop producing dopamine. The lack of dopamine causes the symptoms of Parkinson.

Source: hersenstichting.nl (brain foundation)

Multiple Sclerosis

In case of MS the immune system shows an extremely strong negative response to myeline, a substance naturally produced by the body that produces a layer of isolation on the neurons. This causes the body to stop producing myeline, in its turn stopping the neurons from transmitting the impulses properly. This leads to loss of bodily functions, depending on which part of the brain is affected.

Bron: hersenstichting.nl (brain foundation)

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